Genetic polymorphism of interleukins 6 and 17 correlated with apical periodontitis: A Cross-sectional study.

Interleukins 6 and 17 act in bone resorption in the presence of infections of endodontic origin for host defense. Genetic polymorphisms may be associated with increased bone loss, represented by areas of large periapical lesions. This study aimed to verify the frequency of interleukin 6 and 17 gene polymorphism in patients with asymptomatic apical periodontitis or chronic apical abscess and to verify the existence of correlations between periapical lesion area with age, gender, and presence of the polymorphism, in the studied population, in the state of Pernambuco. A population consisting of thirty diagnosed individuals was included. The area of the lesions was measured in mm². Genomic DNA was extracted and genotyping was performed by Polymerase Chain Reaction Restriction Fragment Length Polymorphism for interleukin 6 (rs 1800795) and interleukin 17 (rs 2275913). Fisher's exact, chi-square, and odds ratio tests were used. A logistic regression analysis was also performed using sex, age, and the presence of polymorphism as covariates, in addition to linear regression to test the relationship between age and lesion area. All tests used a significance level of 0.05% (p ≤0.05%). There was no statistical significance in the occurrence of large areas of periapical lesions correlated with age, sex, and diagnosis, nor in the distribution of alleles in the polymorphism of interleukins 6 and 17 in the studied groups. The frequency of homozygous and heterozygous polymorphism was high. The polymorphism of these interleukins is not correlated with the increase in the areas of asymptomatic periapical inflammatory lesions.

Genetic polymorphism of interleukins 6 and 17 correlated with apical periodontitis: A Cross-sectional study

Abstract Interleukins 6 and 17 act in bone resorption in the presence of infections of endodontic origin for host defense. Genetic polymorphisms may be associated with increased bone loss, represented by areas of large periapical lesions. This study aimed to verify the frequency of interleukin 6 and 17 gene polymorphism in patients with asymptomatic apical periodontitis or chronic apical abscess and to verify the existence of correlations between periapical lesion area with age, gender, and presence of the polymorphism, in the studied population, in the state of Pernambuco. A population consisting of thirty diagnosed individuals was included. The area of the lesions was measured in mm². Genomic DNA was extracted and genotyping was performed by Polymerase Chain Reaction Restriction Fragment Length Polymorphism for interleukin 6 (rs 1800795) and interleukin 17 (rs 2275913). Fisher's exact, chi-square, and odds ratio tests were used. A logistic regression analysis was also performed using sex, age, and the presence of polymorphism as covariates, in addition to linear regression to test the relationship between age and lesion area. All tests used a significance level of 0.05% (p ≤0.05%). There was no statistical significance in the occurrence of large areas of periapical lesions correlated with age, sex, and diagnosis, nor in the distribution of alleles in the polymorphism of interleukins 6 and 17 in the studied groups. The frequency of homozygous and heterozygous polymorphism was high. The polymorphism of these interleukins is not correlated with the increase in the areas of asymptomatic periapical inflammatory lesions.

Resumo As interleucinas 6 e 17 atuam na reabsorção óssea na presença de infecções de oriegem endodôntica para defesa do hospedeiro. Polimorfismos genéticos podem estar associados ao aumento da perda óssea, representada por áreas de lesões periapicais grandes. O objetivo deste estudo foi verificar a frequência do polimorfismo dos genes interleucina 6 e 17 em pacientes com periodontite apical assintomática ou abscesso apical crônico e verificar a existência de correlações entre área de lesão periapical com idade, sexo e presença do polimorfismo, na população estudada, no estado de Pernambuco. Foi incluída uma população constituída por trinta indivíduos diagnosticados. A áreas da lesões foram medidas em mm². O DNA genômico foi extraído e a genotipagem realizada por Polimorfismo de Comprimento de Fragmento de Restrição de Reação em Cadeia da Polimerase para interleucina 6 (rs 1800795) e interleucina 17 (rs 2275913). Os testes exato de Fisher, qui-quadrado e odds ratio foram utilizados. Uma análise de regressão logística também foi realizada usando sexo, idade e presença de polimorfismo como covariável, além de regressão linear para testar a relação da idade e área da lesão. Todos os testes utilizaram um nível de significância de 0,05% (p ≤0.05%). Não houve significância estatística na ocorrência das áreas grandes de lesões periapicais correlacionadas com idade, sexo e diagnóstico nem nas distribuições de alelos no polimorfismo das interleucinas 6 e 17 nos grupos estudados. A frequência de polimorfismo homozigoto e heterozigoto foi alta. O polimorfismo dessas interleucinas não está correlacionado ao aumento das áreas das lesões inflamatórias periapicais assintomáticas.

Perfil clínico-epidemiológico de pacientes pediátricos de um centro de oncohematologia de pernambuco / Clinical-epidemiological profile of pediatric patients at a center of oncohematology in Pernambuco / Perfil clínico-epidemiológico de pacientes pediátricos en un centro de oncohematología de Pernambuco

ntrodução:O câncer infantojuvenil corresponde a um grupo de várias doenças que têm em comum a proliferação descontrolada de células anormais e que pode ocorrer em qualquer local do organismo. Objetivo:Identificar os tipos de neoplasias mais frequentes na infância e adolescência e analisar o perfil clínico-epidemiológicodos pacientes. Metodologia:Estudo de transversal exploratório, de natureza aplicada com análise documental, realizado no Centro de Oncohematologia Pediátrica do Hospital Universitário Oswaldo Cruz, Recife, Pernambuco.Foram incluídos crianças e adolescentes diagnosticados com neoplasia e tratados por terapia antineoplásica.Os critérios de exclusão foram crianças e adolescentes normorreativas e/ou com doenças sistêmicas; prontuários ilegíveis ou com falta de informações clínicas.Resultados:Identificou-se que 54,21% dos pacientes eram dosexo feminino, seguido por 44,86% do sexo masculino.A faixa etária prevalente no estudo foi o de crianças de 5 a 14 anos (54,21%), ainda sobre o perfil dos pacientes, identificou-se que população autodeclarada como negra foi a mais prevalente representando 44,86% do total, seguido dos brancos com 43,93%. O diagnóstico que prevaleceu foi o de Leucemia Linfoide Aguda(23,36%), seguido pela Retinoblastoma (7,48%) e pela Rabdomiossarcoma embrionário (6,54%), e consequentemente o local da neoplasia primária que prevaleceu foi a Medula óssea (27,10%) seguido do olho (10,28%), deste total nota-se que o tratamento antineoplásico mais utilizado foi a quimioterapia (40,19%) seguido da quimioterapia associada à radioterapia(12,15%) e pela quimioterapia associada a cirurgia (10,28%). Conclusões:A leucemia linfoide aguda foi a neoplasia mais frequente na infância e adolescência, com prevalência na idade entre 5 e 14 anos, no sexo feminino e na etnia negra. A terapia antineoplásica mais utilizada foi a quimioterapia, seguida da associação entre quimioterapia e radioterapia (AU).

Introduction:Childhood cancer correspondsto a group of several diseases that have in common the uncontrolled proliferation of abnormal cells and that can occur anywhere in the body. Objective:Identify the most frequent types of neoplasms in childhood and adolescence and analyze the clinical-epidemiological profile of patients. Methodology:Exploratory cross-sectional study, applied in nature with document analysis, carried out at the Pediatric Oncohematology Center of Oswaldo Cruz University, Recife, Pernambuco. Children and adolescents diagnosed with neoplasia and treated with antineoplastic therapy were included. Exclusion criteria were normoreactive children and adolescents and/or with systemic diseases; illegible medical records or lacking clinical information. Results:It was identified that54.21% of the patients were female, followed by 44.86% male. The prevalent age group in the study was children from 5 to 14 years old (54.21%), still regarding the patients'profile , it was identified that the population self-declared as black was the most prevalent, representing 44.86% of the total, followed by of whites with 43.93%. The diagnosis that prevailed was Acute Lymphoid Leukemia (23.36%), followed by Retinoblastoma (7.48%) and Embryonic Rhabdomyosarcoma (6.54%), and consequently,the site of the primary neoplasm that prevailed was Bone marrow (27.10%) followed by the eye (10.28%), of this total it is noted that the most used anticancer treatment was chemotherapy (40.19%) followed by chemotherapy associated with radiotherapy (12.15% ) and chemotherapy associated with surgery (10.28%). Conclusions:Acute lymphoblastic leukemia was the most frequent neoplasm in childhood and adolescence, with a prevalence between 5 and 14 years of age, in females,and black ethnicity. The most used antineoplastic therapy was chemotherapy, followed by the association between chemotherapy and radiotherapy (AU).

ntroducción: El cáncer infantil corresponde a un grupo de varias enfermedades que tienen en común la proliferación descontrolada de células anormales y que pueden presentarse en cualquier parte del cuerpo. Objetivo: Identificar los tipos de neoplasias más frecuentes en la infancia y la adolescencia y analizar el perfil clínico-epidemiológico de los pacientes. Metodología: Estudio transversal exploratorio, aplicado en la naturaleza con análisis de documentos, realizado en el Centro de Oncohematología Pediátrica del Hospital Universitario Oswaldo Cruz, Recife, Pernambuco. Se incluyeron niños y adolescentes con diagnóstico de neoplasia y tratados con terapia antineoplásica. Los criterios de exclusión fueron niños y adolescentes normorreactivos y/o con enfermedades sistémicas; registros médicos ilegibles o carentes de información clínica. Resultados: Se identificó que el 54,21% de los pacientes eran del sexo femenino, seguido del 44,86% del masculino. El grupo etario prevalente en el estudio fueron los niños de 5 a 14 años (54,21%), en cuanto al perfil de los pacientes, se identificó que la población autodeclarada afrodescendiente fue la más prevalente, representando el 44,86% del total, seguido de los blancos con un 43,93%. El diagnóstico que predominó fue Leucemia Linfoide Aguda (23,36%), seguido de Retinoblastoma (7,48%) yRabdomiosarcoma Embrionario (6,54%), y en consecuencia el local de la neoplasia primaria que predominó fue Médula Ósea (27,10%) seguido de ocular (10,28%), de este total se destaca que el tratamiento anticancerígeno más utilizado fue la quimioterapia (40,19%) seguida de la quimioterapia asociada a radioterapia (12,15%) y la quimioterapia asociada a cirugía (10,28%). Conclusiones: La leucemia linfoblástica aguda fue la neoplasia más frecuente en la infancia y la adolescencia, con prevalencia entre los 5 y los 14 años, en el sexo femenino y en la etnia negra. La terapia antineoplásica más utilizada fue la quimioterapia, seguida de la asociación entre quimioterapia y radioterapia (AU).

Incidence and profile of benign epithelial tumors of salivary glands from a single center in Northeast of Brazil

BACKGROUND: Benign tumors of the salivary glands are a group of lesions with varied histopathological and clinical spectrum. The aim was to determine the incidence and clinicopathological characteristics of benign salivary gland neoplasms diagnosed between 2007 and 2016 in a single center located in northeastern Brazil. MATERIAL AND METHODS: Records regarding sex, age, anatomical location, histopathological subtype and treatment were retrieved, and data were analyzed using the Stata/IC software (version 12.0). RESULTS: There were above 7,100 cases of neoplasms in the head and neck region, of which 403 corresponded to salivary gland neoplasms. Of these, 238 (59%) were benign, being pleomorphic adenoma (PA) the most frequent neoplasm (n=178; 74.8%), followed by Warthin's tumor (WT) (n=23; 9.7%). Overall, most cases occurred in females (n=136; 57.1%) and age ranged from 11 to 83 years. The parotid gland (n=188; 79%) was the most common anatomical site, and all patients were treated by surgical excision. Of the cases diagnosed as PA, malignant transformation to carcinoma ex-pleomorphic adenoma (CAEXPA) occurred in 7 (3.9%) cases. CONCLUSIONS: The present study confirmed the clinical and demographic profile of benign salivary gland neoplasms, which contributes to the continuous knowledge of current data about these lesions

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Salivary gland tumors in a Brazilian population: A 20-year retrospective and multicentric study of 2292 cases.

PURPOSE: Neoplasms of the salivary glands comprise more than thirty subtypes of lesions with various clinical behaviors. The present study aimed to describe the incidence and main features of salivary gland tumors in Brazil. MATERIAL AND METHODS: A retrospective descriptive cross-sectional study was performed (1997-2017). A total of 88,430 biopsy records of oral and maxillofacial lesions from 5 pathology referral centers were analyzed. All cases of salivary gland tumors were reviewed and data such as gender, age, skin color, anatomical location, symptomatology, tumor size and histopathological diagnosis were collected. RESULTS: Among all lesions, there were 2,292 (2.6%) cases of salivary gland tumors. The most frequent benign and malignant neoplasm was pleomorphic adenoma (n = 1,086; 47.4%) and mucoepidermoid carcinoma (n = 322; 14.0%), respectively. The majority of the patients were white (n = 757; 33%) and female (n = 1,391; 60.7%), and most cases involved the parotid gland (n = 933; 40.7%; p < 0.001). Age ranged from 1 to 101 years, occurring more in the fourth decade of life. Tumor size varied from 0.3 to 15 cm and the presence of symptomatology (pain/swelling) occurred more in patients with malignant tumors (p < 0.001). CONCLUSION: The incidence profile and clinical findings of salivary gland tumors were similar to those described worldwide; nevertheless, multicenter studies are valuable to better characterize these neoplasms.

A multicenter study of biopsied oral and maxillofacial lesions in a Brazilian pediatric population.

The aim of this study was to investigate the prevalence of oral and maxillofacial lesions among children from representative regions of Brazil. A retrospective descriptive study was conducted. Biopsy records comprising the period from 2000 to 2015 were obtained from the archives of three Brazilian oral pathology referral centers. A total of 32,506 biopsy specimens were analyzed, and specimens from 1,706 children aged 0-12 years were selected. Gender, age, anatomical location and histopathological diagnosis were evaluated. Descriptive statistics was carried out. Likelihood ratio tests were used to evaluate the association between the categorical variables. The level of significance was set at 0.05. The post-hoc test was used to identify the subgroups that significantly differed from one another, and the Bonferroni correction was applied. A total of 1,706 oral and maxillofacial lesions were diagnosed in pediatric patients, including 51.9% girls. Oral mucocele was the most prevalent reactive/inflammatory lesion (64%). The most commonly affected sites were the lips (34.5%) and mandible (19.9%). A significant association was observed between age and the group of lesions of the oral cavity (p < 0.001), and between age and anatomical location (p < 0.001). Pediatric oral and maxillofacial lesions were frequent and showed wide diversity, with the prevalence of mucocele. Knowledge of oral lesions is important for pediatric dentists worldwide, since it provides accurate data for the diagnosis and oral health of children.

A multicenter study of biopsied oral and maxillofacial lesions in a Brazilian pediatric population

Abstract The aim of this study was to investigate the prevalence of oral and maxillofacial lesions among children from representative regions of Brazil. A retrospective descriptive study was conducted. Biopsy records comprising the period from 2000 to 2015 were obtained from the archives of three Brazilian oral pathology referral centers. A total of 32,506 biopsy specimens were analyzed, and specimens from 1,706 children aged 0-12 years were selected. Gender, age, anatomical location and histopathological diagnosis were evaluated. Descriptive statistics was carried out. Likelihood ratio tests were used to evaluate the association between the categorical variables. The level of significance was set at 0.05. The post-hoc test was used to identify the subgroups that significantly differed from one another, and the Bonferroni correction was applied. A total of 1,706 oral and maxillofacial lesions were diagnosed in pediatric patients, including 51.9% girls. Oral mucocele was the most prevalent reactive/inflammatory lesion (64%). The most commonly affected sites were the lips (34.5%) and mandible (19.9%). A significant association was observed between age and the group of lesions of the oral cavity (p < 0.001), and between age and anatomical location (p < 0.001). Pediatric oral and maxillofacial lesions were frequent and showed wide diversity, with the prevalence of mucocele. Knowledge of oral lesions is important for pediatric dentists worldwide, since it provides accurate data for the diagnosis and oral health of children.

Resistance to fracture evaluation of endodontically treated roots of first maxillary premolars

Introduction:One of the most common dental procedures associated to vertical root fractures is the endodontic treatment with excessive dentin wall wear and another increasing risk factor is the use of intraradicular post. Objective: This study evaluated the resistance to fracture of the buccal and palatal roots of maxillary first premolars with endodontically treated canals and spaces for posts. Material and methods: Twenty two first permanent premolar roots (11 buccal and 11 palatal) composed the experimental sample. The canals were prepared with Protaper Universal® system until file F3 and then filled with gutta-percha cone F3 and endodontic sealer and received spaces for posts keeping 4 mm of filling at the apical third. The roots were subjected to compression test in a universal testing machine (Kratus). The roots were subjected to a progressive compression stress at a speed of 0.5 mm / min. A load cell of 200 kg was used. Results: Statistical analysis revealed significant differences between the strength values and resistance limit between groups (P<0.05), as analyzed by t Student test. The values of resistance to fracture of 0.44 kgf/mm2 for group 1 (buccal roots) and 0.31 kgf/mm2 for group 2 (palatal roots) were found. Conclusion: The resistance to fracture of the buccal roots was higher than that of palatal roots of first premolars submitted to biomechanical preparation and root preparation for intraradicular post.

Avaliação de fraturas radiculares em imagens digitais com variações de angulagens / Evaluation of root fracture using digital images with angular

O objetivo da pesquisa foi avaliar a influência da variação da angulagem horizontal no diagnóstico de FRVs em dentes tratados endodonticamente. Vinte e dois pré-molares permanentes com raízes retas e ápices formados foram divididos em grupos: Grupo 01(controle): dois dentes, um deles com núcleo intrarradicular; Grupo 2: dez dentes com fratura; Grupo 3: dez dentes com fratura e núcleo intrarradicular. As amostras foram submetidas a testes de compressão com uma carga de 200 kg a uma velocidade de 0,5 mm / min. Radiografias periapicais foram obtidas (70 kVp, 10 mA, e tempo de exposição de 0,3 seg.) pelo Sistema Digora® em ângulos horizontais, na direção orto radial e com uma mudança de ângulo de 25º para a direita e para a esquerda. As imagens foram avaliadas por cinco endodontistas. O diagnóstico de dentes fraturados e não fraturados foi maior para o 1.º pré-molar (51,66%) que para o 2.º (43,1%). A presença de fratura vertical foi registrada em 60,9% e 66,7% para o 1.º e 2.º prémolares, respectivamente. A presença de fratura mostra associação estatisticamente significante com a presença de núcleo intrarradicular e a variação de angulagem no 2.º pré-molar (p-valor = 0,011). Esses resultados sugerem que variações na angulagem horizontal podem otimizar o diagnóstico de FRVs... (AU)

This study aimed to evaluate the influence of changing horizontal angle during periapical radiography on the diagnosis of VRFs in endodontically treated teeth. Twenty-two single-rooted premolars with straight root canals and apex formation were divided into groups: Group 1 (control) - two non-fractured teeth, one of them with intraradicular post; Group 2 - ten fractured teeth; and Group 3 - ten fractured teeth with intraradicular post. Specimens were subjected to compression testing with a load of 200 kg at a speed of 0.5 mm/min. Periapical radiographs were obtained (70 kVp, 10mA, and 0.3 sec exposure time) in a Digora™ system at horizontal angles in the orthoradial direction and with a 25º angle shift to the right and to the left. Images were evaluated by five endodontists. The diagnosis of fractured and non-fractured roots was higher for the first premolar (51.6%) than for the second premolar (43.1%). The presence of VRFs was recorded in 60.9% of cases for the first premolar, and in 66.7% for the second premolar. Presence of VRFs showed a statistically significant association with presence of intraradicular post and angle variation in the second premolar (p=0.011). These results suggest that changes in horizontal angulation, may optimize the diagnosis of VRFs... (AU)

Evaluation of the nasal shape after orthognathic surgery / Avaliação da forma nasal após cirurgia de avanço e impacção maxilar

Introduction: Patients with dentofacial deformities may benefit from orthognathic surgery in the maxilla. Maxillary osteotomy may include procedures in the bone, cartilaginous, and soft tissues of the nose, leading to shape alterations. Objective: To evaluate the anatomic alterations of the nasal region in patients undergoing a Le Fort I osteotomy for advancement or superior impaction. Methods: This is a clinical prospective study. Twenty-one patients were evaluated during the preand postoperative periods. The positioning of the nasal tip and the modification of the nasal base were evaluated. Results: The results showed that the nasal tip was superiorly positioned in 85% of the cases, advanced in 80%, rotated in 80%, and there was a wide nasal base in 95%, resulting in esthetic improvement. Conclusions: Surgeries of maxillary advancement and superior reposition tend to cause elevation and advancement of the nasal tip, as well as enlargement of the nasal base. .

Introdução: Pacientes com deformidades dento-faciais podem ser beneficiados pela cirurgia ortognática na maxila. A técnica cirúrgica da osteotomia da maxila inclui também procedimentos realizados na parte óssea e cartilaginosa e tecidos moles do nariz o que pode provocar mudanças na forma. Objetivo: Este trabalho teve como proposta avaliar as mudanças anatômicas da região nasal, de correntes de cirurgias maxilares pela osteotomia Le Fort I para avanço e/ou impacção. Método: Trata-se de um estudo clínico prospectivo. Foram incluídos 21 pacientes, submetidos à cirurgia e avaliados antes e 6 meses após o ato cirúrgico em relação aos movimentos da pontanasal e modificações da base do nariz. Resultados: Os resultados mostraram mudanças da ponta nasal para cima em 85% dos casos, para anterior em 80%, rotação em 80% e alargamento da base nasal em 95%, promovendo melhorias estéticas. Conclusão: Cirurgias de avanço e reposicionamento superior da maxila tendem a causa relevação e avanço da ponta do nariz, assim como, um alargamento da base nasal. .

Evaluation of the nasal shape after orthognathic surgery.

INTRODUCTION: Patients with dentofacial deformities may benefit from orthognathic surgery in the maxilla. Maxillary osteotomy may include procedures in the bone, cartilaginous, and soft tissues of the nose, leading to shape alterations. OBJECTIVE: To evaluate the anatomic alterations of the nasal region in patients undergoing a Le Fort I osteotomy for advancement or superior impaction. METHODS: This is a clinical prospective study. Twenty-one patients were evaluated during the pre- and postoperative periods. The positioning of the nasal tip and the modification of the nasal base were evaluated. RESULTS: The results showed that the nasal tip was superiorly positioned in 85% of the cases, advanced in 80%, rotated in 80%, and there was a wide nasal base in 95%, resulting in esthetic improvement. CONCLUSIONS: Surgeries of maxillary advancement and superior reposition tend to cause elevation and advancement of the nasal tip, as well as enlargement of the nasal base.

Tooth Calcification in Low-Weight Human Fetuses / Calcificación de Dientes en Fetos Humanos de Bajo Peso

Tooth calcification begins during the intrauterine life and is related to the nutritional status of fetus. The purpose of this study was to evaluate the dental calcification status of 15 low-weight human fetuses aged from the 14th to 28th weeks of intrauterine life through radiographic analyses and von Kossa histochemical technique, which is specific to the detection of calcium and other mineral salts in tissues. After dissection of jaws, the mandibles were submitted to lateral and occlusal radiographies. Three mm thick slide sections of jaws samples were stained by conventional and von Kossa methods. As results, radiographic analysis did not exhibit any suggestive image of tooth mineralization, although rudiments of mandibular ossification could be noted. Hematoxilin and eosin sections revealed tooth germs in advanced phases of odontogenesis, but relative delay in tooth development was observed. The von Kossa staining did not show any positivity to the deposition of mineral salts in tooth germs from maxilla and mandible, supporting our findings related to the delay of dental development that was found in studied sample. Hence, we suggest that there is relation between the fetal low-weight and the calcification and maturation status of teeth.

La calcificación del diente comienza durante la vida intrauterina y se relaciona con el estado nutricional del feto. El propósito de este estudio fue evaluar el estado de calcificación dental de 15 fetos humanos de bajo peso entre las 14 y 28 semanas de vida intrauterina mediante análisis radiográficos y técnica histoquímica von Kossa, específica para la detección de calcio y otras sales minerales en los tejidos. Después de su disección, las mandíbulas fueron sometidas a radiografías laterales y oclusales. Secciones de 3 mm de espesor de las mandibulas fueron teñidas con la técnica Von Kossa. El análisis radiográfico no mostró ninguna imagen sugerente de mineralización dentaria, aunque rudimentos de la osificación mandibular podrían tenerse en cuenta. Las secciones de H-E revelaron la presencia de los gérmenes dentarios en las fases avanzadas de odontogénesis, pero con un retraso relativo en el desarrollo normal. La tinción de von Kossa no mostró positividad a la deposición de sales minerales en gérmenes dentarios, lo que apoya nuestros hallazgos relacionados con el retraso de desarrollo dental que se encontró en la muestra estudiada. Se sugiere que existe relación entre el bajo peso del feto y el estado de calcificación y maduración de los dientes.

Avaliação subjetiva de artefatos em tomografias computadorizadas de feixe cônico produzidos pelo MTA Fillapex e AH Plus / Subjective evaluation of artifacts in cone beam computed tomography produced by MTA Fillapex and AH Plus

Introdução: O objetivo deste trabalho foi analisar subjetivamente através de um questionário se a radiopacidade dos cimentos endodônticos MTA Fillapex e AH Plus é capaz de produzir artefatos em tomografias computadorizadas de feixe cônico, interferindo na qualidade da imagem e prejudicando o diagnóstico.Métodos: Para tanto, foram formados 1 grupo controle contendo 14 dentes hígidos sem qualquer tratamento endodôntico e 3 grupos experimentais denominados de grupo 1,2 e 3. O grupo 1 conteve 10 dentes testes obturados apenas com guta percha sem cimento endodôntico. O grupo 2 conteve 10 dentes obturados com guta percha embebidas em MTA Fillapex e o grupo 3 apresentou 10 dentes obturados com guta percha associada ao AH Plus. Os grupos foram expostos em um tomógrafo de feixe cônico iCAT a 120Kvp, 37,07mAs, voxel de 0,125mm e tempo de aquisição de 26,9s. As imagens foram salvas em formato xstd e analisadas através do programa XoranCAT por um avaliador especialista em radiologia e endodontia. A avaliação foi feita através de um questionário com perguntas objetivas sobre presença de artefatos, qualidade de imagem nos terços cervical, médio e apical e possibilidade das imagens auxiliarem no correto diagnóstico dos tecidos dentais radiculares Resultados: Os resultados mostraram que houve presença de artefatos em todas as aquisições dos grupos experimentais, assim como 100% das imagens dos grupos experimentais não foram satisfatórias para auxiliarem no correto diagnóstico dos tecidos dentais radiculares. O grupo controle não apresentou artefatos, assim como as imagens foram consideradas satisfatórias para o auxílio de um correto diagnóstico.Conclusões: A tomografia computadorizada de feixe cônico é uma importante ferramenta para o diagnóstico endodôntico. No entanto, assim como outros sistemas de imagens, é passível de falhas...

Introduction: The aim of this study was to analyze subjectively through a questionnaire if the radiopacity of root canal sealers AH Plus and MTA Fillapex is capable of producing artifacts in cone beam computed tomography, interfering with the picture quality and harmingthe diagnosis. Methods: For this purpose, we first formed the control group containing 14 healthy teeth without endodontic treatment and 3groups called Group 1,2 and 3. Group 1 contained 10 test teeth filled with gutta percha without sealer. Group 2 contained 10 teeth filled with gutta percha soaked in Fillapex MTA and group 3 had 10 teeth filled with gutta percha associated with AH Plus. Groups were exposed in a cone beam computed tomography scanner iCAT to 120 kVp, 37.07 mAs , 0.125 mm voxel and acquisition time of 26.9 s . The images were saved as xstd and analyzed with the program XoranCAT by an apprai ser who specializes in radiology and endodontics. The evaluation was conducted through a questionnaire with items about the presence of artifacts, image quality in the cervical, middle and apical third and the possibility of the images assist in correct diagnosis of radicular dental tissues Results: The results showed the presence of artefacts in all acquisitions of the experimental groups, as well as 100 % of the images of the experimental groups were not satisfactory to assist in the correct diagnosis of radicular dental tissues. The control group showed no artifacts, as well as the images were consideredsatisfactory for the assistance of a correct diagnosis. Conclusions:The cone beam computed tomography is an important tool for endodontic diagnosis. How ever, like other imaging systems, is likely to fail. For this reason, the clinical diagnosis should alwaysprevail over the imaging tests, which are supporting the process for acorrect diagnosis.

Facial herpes zoster – case report / Herpes Zóster Facial–Relato de caso

Este artigo descreve um caso de zoster facial o qual afetou um paciente do sexo masculino de dezesseis anos de idade. Suas ulcerações comprometiam a hemiface direita não ultrapassando alinha média facial. Foram realizados a observação e o acompanhamento do paciente durante e após o tratamento. O caso foi acompanhado do aparecimento das lesões até o processo final decicatrização, onde o paciente retornou à sua condição de vida normal.A infecção por herpes zoster parece ser o resultado de um sistema imunológico enfraquecido e os pacientes portadores devem ser monitorados a fim de detectar possíveis sequelas ou doenças oportunistas não diagnosticadas.

This article describes a case of facial zoster which affected a sixteen-year-old male patient. His ulcerations involved the majority of the right hemiface not surpassing the facial midline. The observation of fallow-up of the patient during and after treatment was accomplished and the case was followed up from appearance of the lesion up the final healing process, where the patient had retumed to his normal life condition. Herpes zoster infection seems to be an outcome of a weakened immunologic system and patients must be monitored in order to detect possible sequels or undetected non-diagnosed diseases.

Influência das imagens radiográficas convencional e digital no diagnóstico e decisão de tratamento de cáries proximais / Influence of conventional and digital images on the diagnosis and treatment decisions of interproximal caries

Objetivo: Comparar imagens do sistema digital Digora Fmx®, com placa de fósforo azul, e filme radiográfico Insight®, no diagnóstico de cáries proximais incipientes em esmalte e a sua influência na decisão de tratamento. Método: Foram selecionadas radiografias e imagens digitais de 44 dentes humanos que foram avaliadas, em negatoscópio e monitor de computador sendo atribuídos escores, na presença de cáries e na decisão do tratamento. Para realizar esta avaliação foi selecionado um grupo de 14 alunos do último ano da graduação de odontologia da Faculdade de Odontologia de Pernambuco. A concordância no diagnóstico de cárie foi atestada pelo índice Kappa calculado pela relação entre a sensibilidade e a especificidade e comparada com o padrão ouro. O teste exato de Fisher (p menor que 0,05) foi utilizado para avaliar a influência do diagnóstico na decisão de tratamento. Resultados: Os resultados não mostraram diferenças estatisticamente significativas entre modos de apresentação das imagens quanto ao diagnóstico de cáries proximais em esmalte. Entretanto, as imagens apresentaram-se diferentes do padrão ouro. Na comparação das avaliações radiográficas com a decisão de tratamento observou-se que a conduta de restaurar depende do diagnóstico da extensão da cárie (p menor que 0,001) e não mostrou ter sido influenciada pelo sistema (p=1,000). Conclusão: O sistema digital Digora Fmx®, com a placa de fósforo azul, e o filme radiográfico Insight® demonstraram desempenhos semelhantes na detecção de cáries proximais incipientes; O comprometimento histológico da dentina pela cárie, acarretou no aumento da quantidade de faces corretamente diagnosticadas por meio das modalidades de apresentação das imagens. A decisão de restaurar foi coerente com o diagnóstico da extensão da cárie.

Objective: To compare digital images of the Digora digital system Fmx with blue phosphor plate and the radiographic film Insight, for the diagnosis of incipient interproximal caries in enamel, and their influence on the treatment decision of the lesions. Method: Conventional and digital radiographs of 44 human teeth were selected, and examined on light box and computer screen to attribute scores regarding the presence of caries and treatment decision. Fourteen undergraduate students from the last year of the School of Dentistry of Pernambuco, Brazil, were selected to perform the evaluation. The interexaminer agreement on caries diagnosis was attested by the kappa index, calculated by assessing sensitivity and specificity, and compared with the gold standard. Fisher's exact test (p<0.05) was used to evaluate the influence of diagnosis on treatment decision. Results: No statistically significant differences were found between the radiographic imaging modes regarding the diagnosis of interproximal caries in enamel. However, all images differed from the gold standard. Comparison between the radiographic evaluations and the treatment decision revealed that the choice for restoring the tooth relied on the diagnosis of caries extension (p<0.001), and was not influenced by the radiographic imaging mode (p=1.000). Conclusion: Digora Fmx digital system with blue phosphor plate and the radiographic film Insight showed similar performance for detection of incipient proximal caries. The histological involvement of dentin by caries increased the number of correctly diagnosed tooth surfaces by both radiographic imaging modes. The decision to restore the tooth was consistent with the diagnosis of caries extension.

Avaliação do filtro de luz das câmaras escuras portáteis e de sua influência na qualidade da imagem radiográfica

Introdução: a Portaria 453 do Ministério da Saúde recomenda processar filmes radiográficos intrabucais em câmara escura portátil opaca, sem visor e pelo método temperatura x tempo. Porém, ainda é frequente o processamento pelo método visual em câmaras com visor de polímero de acrílico.O objetivo deste estudo foi avaliar e comparar a capacidade de filtragem de quatro câmaras escuras portáteis (Unemol®,VH®, MPG® e câmara sem identificação) com a de uma câmara escura convencional (controle), e verificar sua influência na qualidade de imagem em diferentes filmes radiográficos (Kodak®: DF-58 Ultra-Speed, E-Speed, IP-21 Insight; e Agfa®Dentus M2). Métodos: os filmes foram expostos junto comum penetrômetro de alumínio e uma placa de chumbo e processados,em soluções Kodak® prontas para uso, em cada câmara portátil e na câmara escura convencional (controle).Os filmes permaneceram três minutos no revelador e a cada minuto eram aproximados do visor, simulando a condição clínica, seguido de banho intermediário e fixação por seis minutos. Foi feita a avaliação fotodensitométrica e os dados foram analisados estatisticamente pelos testes de Mann-Whitneye Kruskal-Wallis. Resultados: o primeiro teste mostrou que, em relação ao grupo controle, somente não houve diferença estatística significativa com a câmara Unemol® quando da utilização dos filmes IP-21 Insight e E-Speed, e com a câmara VH® ao usar o filme IP-21 Insight. O segundo teste mostrou diferença estatística significativa quando da comparação dos filmes entre si. Conclusão: conclui-se que o visor de acrílico aumenta a densidade base e velamento, prejudicando a qualidade da imagem radiográfica

Comparative analysis of the radiopacity of MTA and Portland cement in conventional and digital radiographic systems / Análise Comparativa da Radiopacidade do MTA e Cimento Portland nos Sistemas Radiográficos Digitais e Convencionais

Objetivo: O presente estudo teve como objetivo avaliar a radiopacidade do Agregado de trióxido mineral (MTA) e Cimento Portland (PC) em imagens radiográficas convencionais e digitais a fim de verificar se estão em conformidade com a especificação ANSI / ADA. Materiais e Métodos: Cinco corpos de prova para cada material com 10mm de diâmetro, 1mm de espessura e um penetrômetro foram expostos a 70kVp, 8mA a uma distância foco-filme de 30cm. Os tempos de exposição foram 0,4 e 0,2 s para o filme Insight Kodak e sistema digital CR Kodak 7400, respectivamente. A densidade óptica foi medida na radiografia através de um fotodensitômetro e o valor de pixel foi obtido para as imagens digitais. Um gráfico dos valores obtidos versus mmAl foi elaborado a fim de gerar uma curva de radiopacidade dos degraus do penetrômetro, obtendo a correspondência em equivalência de mmAl dos materiais estudadosUm gráfico foi feito para os valores medidos em comparação mmAl, a fim de gerar uma curva de radiopacidade dos passos penetrômetro, obtendo-se a correspondência de equivalência de mmAl dos materiais estudados. Resultados: O teste estatístico de Mann-Whitney mostrou diferença estatística significativa na radiopacidade entre MTA e PC, tanto no sistema convencional (valor p = 0,009) e digital(valor p = 0,009). O mesmo teste também mostrou diferença estatística significativa entre os sistemas convencionais e digitais em ambos os materiais (p = 0,016 valueMTA-e p-valuecp = 0,009).Conclusões: MTA e CP não apresentaram radiopacidade dentro dos padrões exigidos pela especificação N ○ 57 do American National Standards / American Dental Association.

Objective: The present study aimed to evaluate the radiopacity of Mineral Trioxide Aggregate (MTA) and Portland Cement (PC) in conventional and digital radiographic images in order to verify if they are in accordance with ANSI/ADA specification. Materials and Methods: For each material five test specimens with 10mm of diameter, 1mm of thickness and a stepwedge were exposed at 70kVp, 8mA and focal distance of 30cm. Exposure times were 0,4 and 0,2s for Kodak Insight film and Kodak CR 7400 digital system, respectively. The optic density was measured in the radiograph using a photo-densitometer and the value of pixel was obtained for digital images. A graph was made for measured values versus mmAl in order to generate a radiopacity curve of the stepwedge steps, obtaining the correspondence in equivalence of mmAl of the studied materials. Results: The statistical Mann-Whitney test showed statistical significant difference in the radiopacity between MTA and PC in both conventional (p value = 0,009) and digital (p value = 0,009) systems. The same test also showed statistical significant difference between conventional and digital systems in both materials (p-valueMTA=0,016 and p-valuecp = 0,009). Conclusions: MTA and CP did not show radiopacity inside of the standards demanded by specification N○ 57 of the American National Standards/ American Dental Association.

Avaliação de métodos indiretos de digitalização de radiografias cefalométricas em comparação ao método digital direto / Evaluation of indirect methods of digitization of cephalometric radiographs in comparison with the direct digital method

OBJETIVO: avaliar métodos de digitalização indireta de radiografias cefalométricas em comparação ao método digital direto. MÉTODOS: a amostra foi composta de dez radiografias cefalométricas adquiridas pelo Orthopantomograph OP100/Orthocef OC100 (GE - Instrumentarium), digital direto. As imagens foram inseridas no programa Adobe Photoshop® e cinco pontos cefalométricos foram marcados. Procedeu-se a impressão em transparência e foi feita a digitalização indireta das imagens impressas, por meio das câmeras fotográficas digitais Sony® DSC-W5 e Canon® Rebel XT/EOS 350D, fixas em estativa, nas distâncias de 25cm e 60cm e com o scanner Scan Jet 4C Hewlett Packard®. As imagens diretas e indiretas foram inseridas e calibradas no software Radiocef Studio (Radiomemory®, Brasil), marcando-se o centro dos pontos previamente assinalados. A análise cefalométrica computadorizada gerou três grandezas angulares e quatro lineares, as quais foram submetidas a tratamento estatístico. RESULTADOS: as imagens do scanner Scan Jet 4C HP® demonstraram pequenas alterações significativas, porém, sem relevância clínica. Quando da digitalização a 60cm da radiografia, as duas câmeras causaram distorções que foram significativas mas clinicamente aceitáveis; e, a 25cm, causaram as maiores distorções, com importância clínica, na Canon® Rebel XT. CONCLUSÃO: o scanner Scan Jet 4C HP® com leitor de transparências foi o melhor método e as câmeras operando a 60cm mostraram-se adequadas para digitalização de radiografias. As câmeras na distância de 25cm causaram distorções na imagem que alteraram as medidas lineares, podendo a Canon® Rebel XT comprometer o diagnóstico ortodôntico.

OBJECTIVE: To evaluate the indirect digitization method of cephalometric radiographs in comparison with the direct digital method. METHODS: The sample was composed of ten cephalometric radiographs acquired by Orthopantomograph OP100/Orthocef OC100 (GE - Instrumentarium), digital direct. In the AdobeÕ Photoshop program, five cephalometric landmarks were set in the images and the impression in transparencies was made. The indirect digitization of the images was performed through the SonyÕ DSC-W5 and CanonÕ Rebel XT/EOS 350D digital photographic cameras-fixed in a copy stand, at the distances of 25 cm and 60 cm-and through the Hewlett PackardÕ Scan Jet 4C scanner. The direct digital images and the indirect ones were inserted and gauged in the Radiocef Studio (RadiomemoryÕ, Brazil) software and the center of the previously marked landmarks was set. The cephalometric computerized analysis generated three angular measurements and four linear ones which were submitted to statistical analysis. RESULTS: The images from the scanner demonstrated small statistically significant alterations, without clinical significance. When digitizing the radiographs at 60 cm, both cameras caused distortions which were statistically significant, but clinically acceptable. At 25 cm, the cameras caused the largest distortions, being more expressive and with clinical significance in the images of CanonÕ Rebel XT. CONCLUSIONS: The Hewlett PackardÕ Scan Jet 4C scanner with transparency reader and the SonyÕ DSC-W5 and CanonÕ Rebel XT/EOS cameras operating at 60 cm were shown appropriate for the digitization of cephalometric radiographs. In 25 cm, the digital cameras caused distortions in the image which altered the linear measurements with possibilities of jeopardizing the orthodontic diagnosis.

Aplicação de técnicas radiográficas para o diagnóstico diferencial de tonsilolito / Application of radiographic techniques for differential diagnosis of tonsillolith

A radiografia panorâmica é um dos exames radiográficos mais utilizados na rotina odontológica, existindo grande possibilidade do cirurgião-dentista se deparar com achados radiográficos. Dentre estes, destacam-se as calcificações patológicas encontradas na região de ramo mandibular, tais como sialolito, tonsilolito, calcificações de linfonodos e de vasos sanguíneos. As calcificações patológicas podem possuir aspecto radiográfico semelhante em uma radiografia panorâmica, sendo necessária a complementação com outras técnicas radiográficas a fim de auxiliar no diagnóstico diferencial. Neste trabalho é apresentada uma revisão da literatura a respeito das características radiográficas das calcificações de tecidos moles mais comuns da clínica odontológica. Além disso, é demonstrada a aplicação de técnicas radiográficas no diagnóstico diferencial de tonsilolitos. Diante do exposto, concluiu-se que a associação de técnicas extrabucais é uma importante ferramenta para o preciso diagnóstico de sialolitos, escleroses ósseas e tonsilolitos.

Radiographic image quality after interruption of the fixing stage to view the image with a viewbox / Qualidade da imagem radiográfica quanto ao tempo de leitura em negatoscópio com interrupção da etapa de fixação

Purpose: To evaluate the quality of radiographic images with regard to the time during which the fixing stage was interrupted to allow a preliminary reading of the image in the viewbox. Methods: Radiographs were taken with 130 Insight periapical films, including a step-wedge and lead plate. The films were distributed into 13 groups according to the time taken for reading in a viewbox: 0 (control), 40, 50, 60, 70, 80, 90, 100, 110, 120, 130, 140 and 150 s. During processing using the temperature-time method, the films in the experimental groups were removed 5 s after immersion in the fixer, placed against the light of a viewbox for the studied times and then re-immersed in the fixer to complete the fixation process. Base-plus-fog density and the densities of the first and last degree of the step-wedge were measured immediately and after six months to calculate the contrast. Results: There were no significant differences with regard to the base-plus-fog density or the contrast values of the experimental groups when compared with the control group. Conclusion: It was concluded that interrupting the radiograph fixation process to read the image in a viewbox does not interfere with the base-plus-fog density or with the radiographic contrast, even six months after they were taken.

Objetivo: Avaliar a qualidade da imagem radiográfica quanto ao tempo de leitura em negatoscópio com interrupção da etapa fixação. Metodologia: Foram radiografados 130 filmes periapicais Insight com um penetrômetro e placa de chumbo. Os filmes foram distribuídos em 13 grupos de acordo com o tempo de leitura em negatoscópio: 0 (controle), 40, 50, 60, 70, 80, 90, 100, 110, 120, 130, 140 e 150 s. Durante o processamento pelo método temperatura-tempo, nos grupos experimentais, após 5 s de imersão no fixador, os filmes foram removidos, postos contra a luz de um negatoscópio durante os tempos estudados e imersos no fixador para completar o processo de fixação. Foram mensuradas, imediatamente e após seis meses, as densidades base e velamento e as densidades do primeiro e último degrau do penetrômetro para o cálculo do contraste. Resultados: Não houve diferença significativa em relação aos valores de densidade base e velamento e de contraste das radiografias dos grupos experimentais comparando-os com o grupo controle. Conclusão: Concluiu-se que, durante o processamento das radiografias, os tempos de leitura em negatoscópio não interferiram na densidade base e velamento, nem no contraste radiográfico, mesmo após seis meses de seu arquivamento.